Sanfilippo Growth Impairments Milder Than Other MPS Types

Children with Sanfilippo syndrome have impaired growth compared with the general population, but these deviations are milder than those observed with other types of mucopolysaccharidoses (MPS), a study found. The study, which spanned more than 30 years, found that children with MPS were significantly longer than healthy children at…

Atypical Symptoms Delay Sanfilippo Type B Diagnosis in Mexican Youth

The case of a Mexican youth with Sanfilippo syndrome type B who presented with atypical symptoms of the disease, including growth arrest, sex hormone deficiencies, and a heart defect has been reported by researchers. These previously undescribed manifestations, along with lack of access in Mexico to enzymatic confirmatory tests…

Growth Problems in Sanfilippo Children Milder Than Those Seen in Other MPS Disorders, Study Suggests

Growth impairment among mucopolysaccharidosis (MPS) disorders is milder in people with MPS III (Sanfilippo syndrome) and most profound in those with MPS IVA (Morquio A syndrome), a study in Taiwanese patients suggests. Its findings help in better understanding the characteristic growth patterns of each MPS type,…