Culturing skin cells from patients with Mucopolysaccharidosis IIIB (MPS IIIB) at lower temperatures promotes the production of the active form…
Joana Carvalho, PhD
Joana holds a bachelor’s in biology, a Master of Science in evolutionary and developmental biology, and a PhD in biomedical sciences from Universidade de Lisboa, Portugal. Her work has been focused on the impact of non-canonical Wnt signaling in the collective behavior of endothelial cells — those that make up the lining of blood vessels — found in the umbilical cord of newborns. In addition to several research fellowships, she was awarded two Erasmus scholarships to conduct part of her studies in France.
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Articles by Joana Carvalho, PhD
Stem Cells From MPSIIIA Patient Provide Potentially Useful Tool for Disease Modeling and Therapy
For the first time, researchers have created and validated two lines of stem cells derived from the skin cells of…
Genetic SRT May Be Promising Treatment for Sanfilippo Syndrome, Similar Disorders, Review Finds
Genetic substrate reduction therapy (gSRT) may become a promising new avenue to treat patients with lysosomal storage disorders such as …
Restoring the activity of the alpha-N-acetylglucosaminidase (NAGLU) enzyme using an artificial viral vector successfully corrected metabolic abnormalities in a mouse…